Karina Torres-Castro, Ph.D.

I work at the College of Engineering and Applied Sciences (CEAS) at the State University of New York (SUNY) at Stony Brook, as well as in the Department of Mechanical Engineering. Previously, I was a research associate in the BioMEMS Lab, part of the Biophysical and Biomedical Measurements Group at the National Institute of Standards and Technology NIST. I obtained my Ph.D. in the Charles L. Brown Department of Electrical and Computer Engineering at the University of Virginia, advised by Professor Nathan S. Swami, Biophysical Microsystems Group. I work on developing microfluidic systems to measure various biophysical and/or condensed-matter properties, as well as electrokinetics-based techniques for particle and microstructure manipulation. I received my B.Sc. (Lic.) in Chemical Engineering at the Universidad de Costa Rica and a M.Sc. in Micro-electromechanical systems (MEMS) at the Tecnológico de Costa Rica. Previously, I spent 8 years working as an engineer in the private and public sectors. Email contact: karina.torrescastro@stonybrook.edu

             


Research
Microfluidic Dielectrophoretic Platform for the Manipulation of Brucella abortus Bacteria: Toward Rapid Diagnostic Solutions.
Katherine Acuña-Umana, Estefany García-Martínez, Marco Mairena-Salazar, Nazareth Ruiz-Villalobos, Caterina Guzmán-Verri, Karina Torres-Castro**, Leonardo Lesser-Rojas** ELECTROPHORESIS.
Dielectrophoretic enrichment of live chemo-resistant circulating-like pancreatic cancer cells from media of drug-treated adherent cultures of solid tumors.
Aditya Rane, Javad Jarmoshti, Abdullah Bin-Siddique, Sara Adair, Karina Torres-Castro, Carlos Honrado, Todd W. Bauer, Nathan S. Swami. Lab on a Chip.
Microfluidic Blood Separation: Key Technologies and Critical Figures of Merit.
Karina Torres-Castro, Katherine Acuna-Umana, Leonardo Lesser-Rojas, Darwin R. Reyes. Micromachines. Review
Multichannel Impedance Cytometry Downstream of Cell Separation by Deterministic Lateral Displacement to Quantify Macrophage Enrichment in Heterogeneous Samples.
Karina Torres-Castro, Javad Jarmoshti, Li Xiao, Aditya Rane, Armita Salahi, Li Jin, Xudong Li, Federica Caselli & Carlos Honrado, Nathan S. Swami. Advanced Materials Technologies. -Selected as inside cover-
Biophysical quantification of reorganization dynamics of human pancreatic islets during co-culture with adipose-derived stem cells.
Karina Torres-Castro, Mohammad S. Azimi, Walter B. Varhue, Carlos Honrado, Shayn M. Peirce & Nathan S. Swami. Analyst
On-chip microfluidic buffer swap of biological samples in-line with downstream dielectrophoresis.
XuHai Huang*, Karina Torres-Castro*, Walter Varhue, Aditya Rane, Ahmed Rasin & Nathan S. Swami. ELECTROPHORESIS

*: Equal Contributors    --Best Paper Award! (June 2022)

Thermal Analysis of Microfluidic cooling in Processing-in-3D-Stacked Memory.
Jun-Han Han, Karina Torres-Castro, Robert E. West, Nathan S. Swami & Mircea Stan. 2021 22nd International Conference on Thermal, Mechanical and Multi-Physics Simulation and Experiments in Microelectronics and Microsystems EuroSimE
Power and Thermal Modeling of In-3D-Memory Computing.
Jun-Han Han, Robert E. West, Karina Torres-Castro, Nathan S. Swami, Samira Khan & Mircea Stan. 2021 International Symposium on Devices, Circuits and Systems ISDCS
Self-aligned sequential lateral field non-uniformities over channel depth for high throughput dielectrophoretic cell deflection.
XuHai Huang, Karina Torres-Castro, Walter B. Varhue, Armita Salahi, Ahmed Rasin, Carlos Honrado, Audrey Brown, Jennifer Guler & Nathan S. Swami. Lab on a Chip Lab on a Chip HOT Articles 2021 -Selected as inside front cover-
Microfluidic Cooling for 3D-IC with 3D Printing Package.
Jun-Han Han, Karina Torres-Castro, Robert E. West, Walter B. Varhue, Nathan S. Swami & Mircea Stan. IEEE SOI-3D-Subthreshold Microelectronics Technology Unified Conference S3S
High-throughput dynamical analysis of dielectrophoretic frequency dispersion of single cells based on deflected flow streamlines.
Karina Torres-Castro, Carlos Honrado, Walter B. Varhue, Vahid Farmehini & Nathan S. Swami. Analytical and Bioanalytical Chemistry -Selected as forefront cover-
Combined electrokinetic manipulations of pathogenic bacterial samples in low-cost fabricated dielectrophoretic devices.
Alejandro Martinez-Brenes, Karina Torres-Castro, Richard Marin-Benavides, Katherine Acuña-Umaña, Christopher Espinoza-Araya, Raquel Ramírez-Carranza, Gabriela González-Espinoza, Norman Rojas-Campos, Caterina Guzmán-Verri, Giovanni Sáenz-Arce & Leonardo Lesser-Rojas. AIP Advances
Conferences
MicroTAS (uTAS), Miniaturized Systems for Chemistry and Life Sciences 2025: Real-Time Crossover Cell Migration (COCM) Measurements For Applications in Cancer Biology (Poster)
MicroTAS (uTAS), Miniaturized Systems for Chemistry and Life Sciences 2024: Harmonizing Health Metrics: Microfluidic Surface Acoustic Wave Technology for Measuring Plasma Viscosity (Poster)
ONRG/AFOSR-Costa Rica-Taiwan: Invited speaker at the 1st Advanced Materials Workshop "From Bioinspiration to Technological Innovation"
AES Electrophoresis Society meeting at SciX 2023: Invited speaker in the AES Early career session: On-chip multichannel impedance cytometry for phenotypic monitoring of microfluidic separations
MicroTAS (uTAS), Miniaturized Systems for Chemistry and Life Sciences 2023: Crossover Cell Migration Measurements (CCM): Comprehensive optical and electrical cell tracking (Poster)
Gordon Research Conference (GRC) 2023, Microscale Systems: From Physical Phenomena to Biological Applications: Leveraging multiple surface acoustic waves (SAW) interrogation points for precise flow measurements (Poster)
Gordon Research Seminar (GRS) 2023, Leveraging Microscale Fluidic Phenomena for Novel Analyte Measurements: Leveraging multiple surface acoustic waves (SAW) interrogation points for precise flow measurements (Oral presentation)
Dielectrophoresis 2021: Sidewall electrodes in a microchannel for high-throughput dielectrophoretic separations (Poster)
MicroTAS (uTAS), Miniaturized Systems for Chemistry and Life Sciences 2020: Biomechanical Markers for Monitoring Heterogeneity in Islet Reorganization Dynamics with Adipose Stem Cells (Poster)
AES Electrophoresis Society 2018: Microfluidic Dielectrophoresis Cytometry for Single-Cell Analysis to Quantify Phenotypic Heterogeneity (Poster)
Air Force Office of Scientific Research (AFOSR) Meeting 2017: Aptamer-Based Nanoslit Platforms for Characterizing Human Performance Biomarkers (Oral Presentation)
Dielectrophoresis 2016: Low-cost Fabrication of Dielectrophoretic Devices for Electrokinetic Characterization of Tropical Infectious Bacterial Samples (Poster)
Scientific Peer Review & Technical Advisory Panel Service
BIRD Foundation (Israel-U.S. Binational Industrial Research and Development Foundation).
Analytica Chimica Acta (Elsevier).
ELECTROPHORESIS (Wiley).
Micromachines (MDPI).
Biosensors (MDPI).
Sensors (MDPI).
Awards
Best student paper award -ELECTROPHORESIS- Wiley-VCH (2022).
1st place UVA's ECE Poster competition (2021).
Sture G. Olsson Fellowship in Engineering (2020).
iRedefine Grant Award - NSF Career Development Workshop (2020).
Outstanding Graduate Teaching Assistant Award (2018).
Patent
On-chip Microfluidic Buffer Swap for Biological Samples in-line with Downstream Dielectrophoresis and Related Method Thereof (U.S. Patent App. No. 63/303,717).
Nathan Swami, XuHai Huang, Karina Torres-Castro & Walter Varhue
Teaching
TA: Microfabrication Laboratory 2017-2018.
TA: Fundamentals of Electronics I - Fall 2016.


Work Experience
IguanaSolar
Solar Energy Consultant/Startup.
Mar 2013 - Jun 2016.
CELEQ-UCR.
R&D Engineer .
Mar 2011 - Feb 2015.
Firestone Industrial Products.
Process Engineer.
Jun 2009 - Feb 2011.
Ad Astra Rocket Company.
Intern.
Jan 2009 - May 2009.
Other Publications